pemphigus foliaceus prognosis in cats

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Pemphigus foliaceus is probably the most common autoimmune skin disease in dogs and cats.

. PEMPHIGUS FOLIACEUS IS A RARE autoimmune disease in cats accounting for less than 1 of the authors skin cases. Most PF-affected cats however require long-term treatment and like other autoimmune diseases feline PF has a tendency to relapse spontaneously or with treatment changes. Abstract Feline pemphigus foliaceus is an uncommon skin disorder in cats but still the most common autoimmune skin disorder seen in this species.

Mason K V Day M J 1987 A pemphigus foliaceus-like eruption associated with the use of ampicillin in cat. Many cats with PF require lifelong immunosuppressive therapy. It is a crusting dermatosis involving the ears head paws and ungual folds primarily.

Pemphigus foliaceus in cats diagnosis. Pemphigus foliaceus in cats treatment. Topical therapy for skin conditions in dogs and cats.

The pathomechanism of pf in domestic species to date. Pemphigus Foliaceus Animal Allergy Dermatology Dogs and cats of any age or gender can be affected. Although clinical symptoms can vary affected cats typically develop pustules and crusts on the face inner pinnae and paw pads along with paronychia.

The prognosis of feline PF is good as the majority of cats rapidly achieve disease control even with the most basic treatment such as glucocorticoid monotherapy. Various treatments have been advanced for feline patients with PF. Pemphigus diseases result from the formation of antibodies against keratinocyte structures and differ because each has a different target antigen andor histopathologic feature.

Although cytology is helpful in supporting a diagnosis biopsy of pustules. The prognosis of feline PF is good as the majority of cats rapidly achieve disease control even with the most basic treatment such as glucocorticoid monotherapy. Symptoms of Pemphigus in Cats Pemphigus Foliaceus PF The skin has scales crusts pustules shallow ulcers redness and itching Pads of the paws often have cracking and skin overgrowth Fluid-filled cysts or vesicles in the skin.

In dogs Akitas Chow Chows Doberman Pinschers Dachshunds and Newfoundlands may be predisposed. In cats lesions also develop at the toenail beds creating crusty sore feet. There are two ways that you can treat pemphigus foliaceus and that is by either suppressing your immune system or with medications.

This disease results when the animal recognizes a specific component of his own skin desmoglein I as foreign and makes antibodies against that component. Pemphigus foliaceus prognosis in cats. Key Points Pemphigus foliaceus is a rare autoimmune skin disease that can affect many species.

Pemphigus foliaceus PF although rare in most species is the most commonly reported autoimmune disease in cats Bizikova. As soon as you notice anything at all different about your cats nose topical steroids can provide a lot or relief to your cat. Prognosis The prognosis for pemphigus foliaceus varies between individuals and many cats require lifelong medication.

Pemphigus foliaceus in cats including diagnosis and symptoms pathogenesis prevention treatment prognosis and more. Pemphigus foliaceus may occur spontaneously or be triggered by drugs infections and chronic skin diseases which may have implications for the long-term prognosis. Acantholytic cells caused by degradation of intercellular adhesions are often seen on cytology but are not pathognomonic for PF.

Five receiving ciclosporin plus glucocorticoid and six receiving glucocorticoid monotherapy. No breed predilections exist with cats. Most PF-affected cats however require long-term treatment and like other autoimmune diseases feline PF has a tendency to relapse spontaneously or with treatment changes.

As an autoimmune disease PF may be successfully managed but not cured and the best possible outcome is remission as it is always possible that the disease may recrudesce in the future. Pemphigus foliaceus PF is an immune-mediated disease that causes pustules and crusted lesions most commonly on the pinnae nasal planum periocular area chin and feet of affected cats. It is nevertheless considered to be the most common autoimmune disease of the skin seen in both dogs and cats.

Scott et al 2013Most affected cats are middleaged 58 years with no clear breed or gender predisposition and typically present with yellow to brown adherent crusting skin lesions. Three forms of Pemphigus foliaceus exist in the dog. Pemphigus foliaceus is a severe skin disease that is characterized by pustules and blisters that rupture causing damage to the skin of the face ears feet and eventually the entire skin.

Pemphigus Foliaceus The Skin Vet